How Enclomiphene Can Help Boost Testosterone

Testosterone is the hormone that is largely responsible for men being able to maintain an energetic life with a healthy sex drive. Increasing testosterone levels in the most natural ways possible has become popular and important for men as they age. This article will explain how Enclomiphene for men works as a natural testosterone booster.

What is Enclomiphene?

Enclomiphene is one of two isomers found in Clomiphene citrate, commonly known as Clomid. It’s characterized by its anti-estrogenic effects. This attribute plays a crucial role in its therapeutic benefits, particularly for treating men with low testosterone. 

Clomiphene citrate, the precursor to Enclomiphene, was approved by the FDA in 1976 under the brand name Clomid. It was initially used as a fertility drug for stimulating ovulation in women. It then became popular for its off-label use in boosting testosterone levels in men.

Over time, research showed that isolating the Enclomiphene isomer within Clomid was a more effective and safer way to help regulate testosterone in males. 

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How Does Enclomiphene Work?

Enclomiphene works as a selective estrogen receptor modulator (SERM). This means it stops estrogen from binding with the hypothalamus and pituitary gland in the brain. This blockage leads to an increase in the release of gonadotropin-releasing hormone (GnRH).

Increased levels of GnRH encourage the pituitary gland to produce more luteinizing hormones (LH) and follicle-stimulating hormones (FSH). LH stimulates the testes to produce more testosterone in men, increasing overall levels. 

Benefits of Enclomiphene Therapy

There are several benefits of using Enclomiphene for men with lower testosterone levels. It can work well for anyone who wants to increase their levels, but it works particularly well for men under 40.

Revitalizes Energy 

The increase in testosterone due to Enclomiphene results in rejuvenated energy levels. This allows you to keep playing sports for longer and with the same vigor as your younger self. You will find energy improvements that give you longer stamina and increased strength.

Enhances Libido

The strength and endurance gains are not limited to the sports realm. Increases in testosterone also help to improve sex drive. This helps to rebuild emotional connections and strengthen romantic relationships that may have been strained due to a lack of intimacy. 

Combats Depression

Low testosterone is often linked with depression. The knock-on effects of lack of energy and lowered sex drive combine to create a perfect recipe for low mood and negative thoughts. It’s been shown that a higher level of testosterone promotes positive mood and improves confidence, helping to combat depression in men.

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Enclomiphene vs. Other Treatment Options

Let’s see how Enclomiphene stacks up against other testosterone options.

Testosterone Replacement Therapy (TRT)

TRT introduces synthetic testosterone into the body to raise levels. This synthetic testosterone production can lead to your body shutting down its own production, causing testicles to shrink and affecting fertility by reducing sperm production. This means that Enclomiphene may be the better option for men under 40 who want to retain their fertility if they are planning on having children.

Human Chorionic Gonadotropin (hCG)

hCG mimics LH to stimulate the production of testosterone internally. While it is good that exogenous testosterone is not needed, hCG has two disadvantages when compared to Enclomiphene. 

The first is that it needs to be injected, whereas Enclomiphene can be taken orally. The second is that Enclomiphene’s targeted action on estrogen receptors ensures a more balanced hormonal response. 

Potential Side Effects

The most commonly reported side effects of taking Enclomiphene are mild cases of headaches, nausea, and joint pain. These symptoms were reportedly so mild that they didn’t interfere with daily activities or exercise.

Some men also report gastrointestinal discomfort, which can be a particular concern for those who are following a strict diet.

Unlike TRT, Enclomiphene does not typically cause testicular shrinkage, but in rare cases, it may cause a change in testicle size. 

Some men may experience fluctuations in their libido. These instances are usually infrequent and not severe. There may also be some fluctuations in the mood of men who are sensitive to hormonal changes. 

Although Enclomiphene is generally considered safe for long-term use, regular medical checkups are advised. 

Consult a Professional 

If you want to check your testosterone levels to see if you, too, could benefit from Enclomiphene, get in touch with one of our experts today

No need to visit our clinics and wait around to be seen. You will start with a video call with one of our doctors. Once we have created the perfect plan for you, everything can be taken care of from the comfort of your home. 


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If you’re experiencing symptoms of low T, reach out to our team to find out how we can help you. 

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