Testosterone is a hormone that plays a key role in various aspects of men’s health, including energy levels and sexual function. As men age, testosterone levels may naturally decline.
Enclomiphene is a treatment option that may be considered for men experiencing low testosterone levels. This article will explain how Enclomiphene is used to support testosterone production and its potential role as part of a medically supervised treatment plan.
What is Enclomiphene?
Enclomiphene is one of two isomers found in Clomiphene citrate, commonly known as Clomid. It’s characterized by its anti-estrogenic effects. This attribute plays a crucial role in its therapeutic benefits, particularly for treating men with low testosterone.
Clomiphene citrate, the precursor to Enclomiphene, was approved by the FDA in 1976 under the brand name Clomid. It was initially used as a fertility drug for stimulating ovulation in women. It then became popular for its off-label use in boosting testosterone levels in men.
Over time, research showed that isolating the Enclomiphene isomer within Clomid was a more effective and safer way to help regulate testosterone in males.
How Does Enclomiphene Work?
Enclomiphene works as a selective estrogen receptor modulator (SERM). This means it stops estrogen from binding with the hypothalamus and pituitary gland in the brain. This blockage leads to an increase in the release of gonadotropin-releasing hormone (GnRH).
Increased levels of GnRH encourage the pituitary gland to produce more luteinizing hormones (LH) and follicle-stimulating hormones (FSH). LH stimulates the testes to produce more testosterone in men, increasing overall levels.
Potential Benefits of Enclomiphene Therapy
Enclomiphene therapy is an option that some healthcare providers may recommend for men with low testosterone levels. It is often considered for younger men, including those under 40, who may be seeking an alternative to traditional testosterone replacement therapies. As with any medical treatment, the use of Enclomiphene should be guided by a licensed healthcare professional, and individual results may vary.
Supporting Energy Levels
Low testosterone may contribute to feelings of fatigue or decreased stamina. By helping to support testosterone production, Enclomiphene therapy may improve energy levels. However, the extent of these improvements varies from person to person, and they depend on many factors, including overall health and lifestyle.
Potential Effects on Libido
Healthy testosterone levels can play a role in maintaining sexual health and libido. Men undergoing Enclomiphene therapy may notice changes in this area, which could contribute to their overall well-being. It is important to discuss expectations and potential outcomes with your healthcare provider.
Mood and Emotional Health
Some studies suggest that low testosterone may be associated with mood changes, including symptoms of depression. By addressing low testosterone levels, Enclomiphene therapy may have an impact on mood and confidence. However, managing mood disorders often requires a comprehensive approach, and therapy should be part of a broader plan under medical supervision.
Enclomiphene vs. Other Treatment Options
Let’s see how Enclomiphene stacks up against other testosterone options.
Testosterone Replacement Therapy (TRT)
TRT introduces synthetic testosterone into the body to raise levels. This synthetic testosterone production can lead to your body shutting down its own production, causing testicles to shrink and affecting fertility by reducing sperm production. This means that Enclomiphene may be the better option for men under 40 who want to retain their fertility if they are planning on having children.
Human Chorionic Gonadotropin (hCG)
hCG mimics LH to stimulate the production of testosterone internally. While it is good that exogenous testosterone is not needed, hCG has two disadvantages when compared to Enclomiphene.
The first is that it needs to be injected, whereas Enclomiphene can be taken orally. The second is that Enclomiphene’s targeted action on estrogen receptors ensures a more balanced hormonal response.
Potential Side Effects
The most commonly reported side effects of taking Enclomiphene are mild cases of headaches, nausea, and joint pain. These symptoms were reportedly so mild that they didn’t interfere with daily activities or exercise.
Some men also report gastrointestinal discomfort, which can be a particular concern for those who are following a strict diet.
Unlike TRT, Enclomiphene does not typically cause testicular shrinkage, but in rare cases, it may cause a change in testicle size.
Some men may experience fluctuations in their libido. These instances are usually infrequent and not severe. There may also be some fluctuations in the mood of men who are sensitive to hormonal changes.
Although Enclomiphene is generally considered safe for long-term use, regular medical checkups are advised.
Consult a Professional
If you want to check your testosterone levels to see if you, too, could benefit from Enclomiphene, get in touch with one of our experts today.
At Men’s Revival, We Do It Right. Phlebotomists come to you for your blood draws, and doctor visits can be in-person at our office or over telemedicine.
FAQs
Enclomiphene is primarily used for treating low testosterone levels in males — a condition known as hypogonadism.
This depends on several factors, including age, overall health, and baseline testosterone levels, which influence the extent of the increase. Enclomiphene has been shown to bring testosterone levels back to normal in men with low testosterone.
Enclomiphene has several advantages over TRT. As it encourages the body to produce testosterone naturally, it will not affect your body’s ability to produce testosterone by itself in the future. Enclomiphene also does not shrink the testicles, nor does it affect fertility like TRT does.
Ready to take the next step?
If you’re experiencing symptoms of low T, reach out to our team to find out how we can help you.