Tirzepatide vs Semaglutide for Weight Loss
Let’s face it: You’re curious about the new slew of weight loss drugs on the market. We can hear you denying it, protesting that you’re a grown man and not a Kardashian. But if you’re carrying excess body fat, you know all too well that losing it can be a real pain. Between cutting out alcohol and sugar and surviving on a seemingly endless diet of plain chicken and vegetables, trying to lose body fat can feel like never-ending torture. So, you see one of those annoying commercials on TV. You see an actress on Instagram talking about how yoga and meditation took her from the funny best friend roles to leading lady material when you know that her so-called zen came in a little syringe. Understandably, you’re starting to think, “If everyone else is getting a shortcut, why can’t I?” Well, we have some good news for you. As one of Scottsdale’s leading men’s clinics, we’re thrilled to offer tirzepatide and semaglutide to medically suitable candidates. However, before you say “I’ll have ten injections of skinny, please,” it’s important that you understand what you’re getting yourself into. Here’s what to know about tirzepatide and semaglutide.
22 May 2025 • 4 min read
TABLE OF CONTENT
TABLE OF CONTENT
Understanding the New Thought Processes Surrounding Overweight and Obesity
Like anyone passionate about men’s health, the staff at Men’s Revival believed most of the bro science that we now know to be complete BS about obesity. Fat dudes were fat because they were gluttonous, actively choosing to wolf down four extra slices of meatloaf even after they were plenty satiated. Lean dudes were marvels of discipline and self-control, constantly battling hunger in favor of having washboard abs. Remember your college roommate who had the body of an Olympic swimmer without putting any effort into maintaining it? Somehow, despite not being able to write a one-page essay without procrastinating until 15 minutes before class, he had the discipline of a Navy Seal when it came to food. Go figure. We realized a while ago that the concept of some people simply having “fast metabolisms” was mostly bogus, so the bro science was the only explanation that made sense. After all, if weight loss or gain comes down to calories in and calories out, some people must just be able to control themselves better than others. However, we were so quick to assume that the issue had to be one of self-control that we never stopped to consider that maybe some people are just way, way hungrier than others. Maybe you’ve noticed it when you’re around your skinnier friends. You guys order the same thing, but while your lean friend seems good to go after six chicken wings, you’re still craving seconds after the basket’s empty, insisting that 25 cents a wing is just too good of a bargain to not indulge. Despite your cover story, you’re hungry. You don’t understand how your buddies have moved on to darts when you’re still starving. The good news is that you’re not ravenously hungry because of some fat guy curse. Rather, your hormones and insulin might not be functioning properly, whereas those of your “naturally lean” friends do. This is where a men’s health clinic can help.
How Tirzepatide Can Help
When you eat, your body releases two hormones: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). These hormones tell your brain that you’re full and send a signal to your pancreas to release insulin, thereby lowering your blood sugar and ending that feeling like you might faint if you don’t get some food in your stomach. The new thought process is that those struggling with obesity or excess body weight might have lazy hormone receptors that don’t properly release these hormones. Thus, your body never gets the signal that you’re full and suddenly $50 worth of Taco Bell sounds like a reasonable lunch option. Tirzepatide works by activating these two hormone receptors, prompting them to kick it into gear. With these hormone receptors functioning properly, you’ll feel fuller quicker and will enjoy regular blood sugar levels after a meal. With that ravenous urge to eat more gone, you’ll have an easier time losing weight than when you were trying to white-knuckle it with sheer willpower alone.
How Semaglutide Can Help
Semaglutide works a little differently than tirzepatide. It mimics the body’s glucagon-like peptide-1 (GLP-1) and slows down the rate at which food leaves the stomach and enters the small intestine.. This delayed gastric emptying leads to a prolonged sense of fullness making it easier to no longer crave that infamous 4th meal. If you’ve heard the commercials with the obnoxious “oh-oh-oh” jingle, that’s semaglutide. The “O” word that seems to be on everyone’s lips (instead of, you know, food) has led most of us to assume that semaglutide is the ideal choice out of the two options. After all, if it’s good for Hollywood stars, then surely it has to be the best course of action for us mere mortals. However, the medical literature doesn’t necessarily support this.
The Advantages of Tirzepatide
Some studies have shown that tirzepatide has slightly more promising results when it comes to producing medically significant weight loss. Our medical team tends to prefer it and has seen positive results in our clients who are currently on it. One of the advantages is that tirzepatide works on both GIP and GLP-1, whereas semaglutide only works on GLP-1. However, cases may vary, and your health professional may determine that semaglutide is more appropriate for your specific needs.
“Enough science. Stick me, Doc.”
Not so fast. Just as we do when it comes to prescribing testosterone replacement therapy, we don’t just hand out tirzepatide or semaglutide to anyone. You will need to go through a medical screening and in the vast majority of cases, the drug can only be prescribed if you are medically overweight. (For the lean guys looking to take off five vanity pounds, we recommend good old-fashioned dessert-skipping.) The drug does come with some risks and side effects, which your provider will walk you through during your appointment. It’s important to answer any questions about your current health honestly to ensure that tirzepatide or semaglutide is indeed appropriate for your individual medical needs. While it should be obvious, it’s also important to highlight one important thing about these weight loss drugs: There is no magic bullet. While tirzepatide and semaglutide can help majorly in putting you on the right track, diet and lifestyle changes are essential. These drugs will make it easier to resist temptation, but our medical team needs you to commit to making an overhaul. While change can be hard, the good news is that as you see the pounds come off, your energy become heightened, and your libido restored to that of your glory days, you’ll likely have the motivation to keep up the positive changes. If you’re not sure where to begin, our team will get you on the right track and guide you toward the appropriate lifestyle changes. It might be time to kiss the Big Macs goodbye, but the good news is that you’re trading them in for more active adventures.
The Smart Choice for Men’s Health in Scottsdale
At Men’s Revival, we pride ourselves on being one of the top choices that men in Scottsdale can make for their health. We’ve proudly offered testosterone replacement therapy to scores of satisfied clients and we’re thrilled to be able to offer tirzepatide and semaglutide to men struggling with their weight. Much as we do when it comes to prescribing TRT, we follow rigorous health standards to ensure you’re a good candidate and offer ongoing support and access to our medical professionals. We allow you to access the medical intervention you need, from the comfort of your own home and on your schedule.
Ready to take the next step?
If you’re ready to feel your best, reach out to our team to find out how we can help you.